FBXO33

Across TCGA patient cohorts, FBXO33 mutation is significantly associated with the RNA expression of many other genes, with 1,631 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO33-associated genes across cancer lineages are HIGD1AP13, RNA5SP411, and MIR4686. Each is linked with FBXO33 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO33-to-partner and partner-to-FBXO33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HIGD1AP13 grouped by FBXO33-low versus FBXO33-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO33→partner) and Y-score (partner→FBXO33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	HIGD1AP13 →	+0.139	+5.342	<.001	.002	3	2
UCEC	RNA5SP411 →	+1.012	+1.978	<.001	.002	3	2
BRCA	MIR4686 →	+0.950	+5.153	<.001	.001	3	2
SKCM	RN7SL554P →	+0.171	+6.199	<.001	.001	3	2
UCEC	RNA5SP413 →	+1.439	+2.692	<.001	<.001	3	2
BRCA	MIR4726 →	+0.736	+5.382	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,631 associations by consensus.

HIGD1AP13 by FBXO33 expression — CESC

Explore this box plot interactively →