FBXO33

Across TCGA cell cohorts, FBXO33 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,313 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO33-associated GO terms across cancer lineages are Golgi organization, Piecemeal microautophagy of the nucleus, and Regulation of transforming growth factor beta receptor signaling pathway. Each is linked with FBXO33 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBXO33-to-partner and partner-to-FBXO33 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by FBXO33-low versus FBXO33-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO33→partner) and Y-score (partner→FBXO33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Golgi organization →	+0.051	+0.473	<.001	.001	3	12
SOFT_TISSUE	Piecemeal microautophagy of the nucleus →	+0.051	+0.620	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of transforming growth factor beta receptor signaling pathway →	+0.051	+0.728	.006	.002	3	11
URINARY_TRACT	Phosphatidylinositol metabolic process →	+0.058	+1.059	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of stem cell population maintenance →	+0.088	+0.768	.002	<.001	3	11
OESOPHAGUS	Actin filament fragmentation →	+0.145	+0.776	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,313 associations by consensus.

Golgi organization by FBXO33 expression — LARGE_INTESTINE

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