FBXO32

Across TCGA patient cohorts, FBXO32 protein abundance is significantly associated with the RNA expression of many other genes, with 858 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXO32-associated genes across cancer lineages are ARHGEF33, GGCTP1, and PRLR. Each is linked with FBXO32 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO32-to-partner and partner-to-FBXO32 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO32 versus ARHGEF33 in LUAD, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO32→partner) and Y-score (partner→FBXO32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ARHGEF33 →	-1.016	-0.406	<.001	.002	3	2
LUAD	GGCTP1 →	-1.108	-0.308	.003	.004	3	2
UCEC	PRLR →	-2.547	-0.944	.008	.007	3	1
UCEC	ACVR2A →	-0.580	-1.330	.005	.006	3	1
UCEC	PHF10 →	+0.629	+1.129	.007	.007	3	1
UCEC	ESPL1 →	+1.339	+1.330	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 858 associations by consensus.

FBXO32 vs ARHGEF33 — LUAD

Explore this scatter interactively →