FBXO32

Across TCGA cell cohorts, FBXO32 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,315 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FBXO32-associated GO terms across cancer lineages are Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process, Response to denervation involved in regulation of muscle adaptation, and Regulation of proteolysis. Each is linked with FBXO32 in more than 16 cancer types. Because this analysis shows association rather than direction, both FBXO32-to-partner and partner-to-FBXO32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process grouped by FBXO32-low versus FBXO32-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO32→partner) and Y-score (partner→FBXO32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process →	+0.205	+3.405	<.001	<.001	3	17
BLOOD_Leukemia	Response to denervation involved in regulation of muscle adaptation →	+0.568	+0.780	<.001	.001	3	13
BONE	Regulation of proteolysis →	+0.099	+1.922	.001	.004	3	13
KIDNEY	Wound healing →	+0.122	+1.989	<.001	.003	2	14
KIDNEY	Regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	+0.157	+2.807	<.001	<.001	3	13
SOFT_TISSUE	Negative regulation of cytokine production →	+0.085	+2.775	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,315 associations by consensus.

Negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process by FBXO32 expression — KIDNEY

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