FBXO3

Across TCGA patient cohorts, FBXO3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,446 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FBXO3-associated genes across cancer lineages are UBE2C, CDKN3, and CENPI. Each is linked with FBXO3 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXO3-to-partner and partner-to-FBXO3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO3 versus UBE2C in LUAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO3→partner) and Y-score (partner→FBXO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	UBE2C →	-1.163	-0.153	<.001	<.001	3	5
UCEC	CDKN3 →	-0.943	-0.323	<.001	<.001	3	4
LUAD	CENPI →	-0.778	-0.158	<.001	<.001	3	4
LUAD	HLF →	+1.375	+0.200	<.001	<.001	3	4
GBM	ELP4 →	+0.378	+0.280	.001	.002	3	4
LUAD	FBXO5 →	-0.637	-0.162	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,446 associations by consensus.

FBXO3 vs UBE2C — LUAD

Explore this scatter interactively →