FBXO3

Across TCGA cell cohorts, FBXO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,117 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO3-associated GO terms across cancer lineages are Golgi organization, Autophagosome assembly, and Autophagy. Each is linked with FBXO3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBXO3-to-partner and partner-to-FBXO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi organization grouped by FBXO3-low versus FBXO3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO3→partner) and Y-score (partner→FBXO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Golgi organization →	+0.066	+0.881	<.001	<.001	3	12
LARGE_INTESTINE	Autophagosome assembly →	+0.061	+0.818	<.001	<.001	3	12
LARGE_INTESTINE	Autophagy →	+0.051	+0.628	<.001	.001	3	11
BREAST	Golgi vesicle transport →	+0.052	+0.787	.003	<.001	3	11
LARGE_INTESTINE	Process utilizing autophagic mechanism →	+0.051	+0.628	<.001	.001	3	11
BLOOD_Lymphoma	Monoubiquitinated protein deubiquitination →	+0.081	+0.914	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,117 associations by consensus.

Golgi organization by FBXO3 expression — LARGE_INTESTINE

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