FBXO27

Across TCGA patient cohorts, FBXO27 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,150 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO27-associated proteins across cancer lineages are GSTM2, UCHL1, and MAPRE3. Each is linked with FBXO27 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXO27-to-partner and partner-to-FBXO27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO27 versus GSTM2 in LSCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO27→partner) and Y-score (partner→FBXO27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GSTM2 →	+1.077	+1.204	<.001	<.001	3	5
HNSC	UCHL1 →	+0.912	+0.720	.003	.002	3	5
GBM	MAPRE3 →	+0.393	+0.464	<.001	<.001	3	5
HNSC	TRIM2 →	+0.649	+0.848	<.001	<.001	3	5
OV	CDK5 →	+0.374	+1.000	.001	.001	3	4
UCEC	GMDS →	-0.736	-0.792	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,150 associations by consensus.

FBXO27 vs GSTM2 — LSCC

Explore this scatter interactively →