FBXO27

Across TCGA patient cohorts, FBXO27 protein abundance is significantly associated with the RNA expression of many other genes, with 829 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXO27-associated genes across cancer lineages are ZNF565, STYK1, and DNAJC12. Each is linked with FBXO27 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO27-to-partner and partner-to-FBXO27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO27 versus ZNF565 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO27→partner) and Y-score (partner→FBXO27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZNF565 →	+0.575	+0.888	.003	<.001	3	2
LSCC	STYK1 →	+0.627	+0.550	.009	.006	3	2
HNSC	DNAJC12 →	-0.694	-0.428	.004	.007	3	1
HNSC	FOXA2 →	-1.217	-0.498	<.001	.001	3	1
HNSC	RAP1GAP2 →	-0.606	-0.696	.004	.001	3	1
HNSC	C10orf82 →	-0.496	-0.512	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 829 associations by consensus.

FBXO27 vs ZNF565 — LSCC

Explore this scatter interactively →