FBXO25

Across TCGA cell cohorts, FBXO25 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXO25-associated genes across cancer lineages are OR10V1, IL9, and PROP1. Each is linked with FBXO25 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO25-to-partner and partner-to-FBXO25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10V1 grouped by FBXO25-low versus FBXO25-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO25→partner) and Y-score (partner→FBXO25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR10V1 →	+0.036	+5.000	<.001	.006	3	1
BLOOD_Leukemia	IL9 →	+0.145	+4.539	<.001	.007	3	1
BLOOD_Leukemia	PROP1 →	+0.024	+4.874	.002	.002	3	1
BLOOD_Leukemia	SPATA31A7 →	+0.028	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR10V1 by FBXO25 expression — PANCREAS

Explore this box plot interactively →