FBXO2

Across TCGA patient cohorts, FBXO2 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXO2-associated genes across cancer lineages are MIR6774, MIR6771, and OR7E18P. Each is linked with FBXO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXO2-to-partner and partner-to-FBXO2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6774 grouped by FBXO2-low versus FBXO2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO2→partner) and Y-score (partner→FBXO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6774 →	+0.841	+4.475	.004	.002	3	1
UCEC	MIR6771 →	+0.568	+4.538	<.001	.006	3	1
UCEC	OR7E18P →	+0.063	+4.442	.001	.007	3	1
UCEC	RNY4P27 →	+0.354	+4.868	<.001	.004	3	1
UCEC	RNA5SP393 →	+0.977	+5.351	<.001	<.001	3	1
UCEC	RNU1-1 →	+0.539	+4.386	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR6774 by FBXO2 expression — UCEC

Explore this box plot interactively →