FBXO17

Across TCGA patient cohorts, FBXO17 protein abundance is significantly associated with the RNA expression of many other genes, with 4,083 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FBXO17-associated genes across cancer lineages are NLGN1-AS1, FERMT2, and RIPK3. Each is linked with FBXO17 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXO17-to-partner and partner-to-FBXO17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXO17 versus NLGN1-AS1 in CCRCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXO17→partner) and Y-score (partner→FBXO17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NLGN1-AS1 →	+1.210	+0.475	<.001	.001	3	3
LSCC	FERMT2 →	+1.096	+0.656	<.001	<.001	3	3
GBM	RIPK3 →	-0.745	-0.884	.001	<.001	3	3
CCRCC	ERVK9-11 →	+0.943	+0.471	.004	.001	3	3
UCEC	KATNAL1 →	+0.824	+0.963	<.001	<.001	3	2
UCEC	OLFM2 →	+1.081	+0.905	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,083 associations by consensus.

FBXO17 vs NLGN1-AS1 — CCRCC

Explore this scatter interactively →