FBXL8

Across TCGA patient cohorts, FBXL8 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,343 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXL8-associated proteins across cancer lineages are NOL3, EPHB3, and CCDC88B_S1379. Each is linked with FBXL8 in more than 5 cancer types. Because this analysis shows association rather than direction, both FBXL8-to-partner and partner-to-FBXL8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL8 versus NOL3 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL8→partner) and Y-score (partner→FBXL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NOL3 →	+0.725	+0.643	<.001	.001	3	6
UCEC	EPHB3 →	+0.760	+0.632	.009	.004	3	5
CCRCC	CCDC88B_S1379 →	-0.585	-0.550	.005	<.001	3	4
UCEC	CTNNA1 →	+0.318	+0.559	<.001	.002	3	4
LSCC	DHX38 →	+0.190	+0.452	<.001	<.001	3	4
LSCC	EDC4 →	+0.205	+0.492	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,343 associations by consensus.

FBXL8 vs NOL3 — OV

Explore this scatter interactively →