FBXL8

Across TCGA cell cohorts, FBXL8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,367 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FBXL8-associated GO terms across cancer lineages are Cilium or flagellum-dependent cell motility, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with FBXL8 in more than 16 cancer types. Because this analysis shows association rather than direction, both FBXL8-to-partner and partner-to-FBXL8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium or flagellum-dependent cell motility grouped by FBXL8-low versus FBXL8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL8→partner) and Y-score (partner→FBXL8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.114	-1.370	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.114	-1.370	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.119	-1.370	<.001	<.001	3	16
KIDNEY	Establishment of meiotic sister chromatid cohesion →	-0.212	-0.992	.004	.004	3	15
BONE	Viral transcription →	+0.115	+1.390	<.001	<.001	3	15
LARGE_INTESTINE	mRNA splice site recognition →	+0.131	+1.204	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,367 associations by consensus.

Cilium or flagellum-dependent cell motility by FBXL8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →