FBXL3

Across TCGA cell cohorts, FBXL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,839 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FBXL3-associated GO terms across cancer lineages are Phosphatidylinositol dephosphorylation, Positive regulation of cytoplasmic mRNA processing body assembly, and Protein desumoylation. Each is linked with FBXL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBXL3-to-partner and partner-to-FBXL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol dephosphorylation grouped by FBXL3-low versus FBXL3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL3→partner) and Y-score (partner→FBXL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Phosphatidylinositol dephosphorylation →	+0.070	+0.630	<.001	.001	3	12
BLOOD_Leukemia	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.091	+0.506	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein desumoylation →	+0.083	+0.919	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Ribosomal protein import into nucleus →	+0.088	+0.633	<.001	<.001	3	11
STOMACH	Phosphatidylinositol biosynthetic process →	+0.068	+0.521	<.001	.006	3	11
LIVER	Positive regulation of post-translational protein modification →	+0.061	+0.673	.005	.004	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,839 associations by consensus.

Phosphatidylinositol dephosphorylation by FBXL3 expression — STOMACH

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