Across TCGA patient cohorts, FBXL22 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,433 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBXL22-associated proteins across cancer lineages are CNN3, MYH10, and ACTN1. Each is linked with FBXL22 in more than 7 cancer types. Because this analysis shows association rather than direction, both FBXL22-to-partner and partner-to-FBXL22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL22→partner) and Y-score (partner→FBXL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CNN3 →	+0.546	+0.713	<.001	<.001	3	8
COAD	MYH10 →	+0.693	+0.301	<.001	.009	3	8
UCEC	ACTN1 →	+0.479	+0.655	<.001	<.001	3	7
PDAC	EFEMP2 →	+0.752	+0.373	<.001	.001	3	7
CCRCC	FHL3 →	+0.723	+0.410	<.001	<.001	3	7
UCEC	FILIP1L →	+0.617	+0.639	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,433 associations by consensus.

Exploration

FBXL22 survival (RNA) · tumor vs normal (RNA) · all FBXL22 data types