Across TCGA patient cohorts, FBXL22 protein abundance is significantly associated with the RNA expression of many other genes, with 853 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXL22-associated genes across cancer lineages are POLR3H, TRIM9, and AHCY. Each is linked with FBXL22 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL22-to-partner and partner-to-FBXL22 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL22→partner) and Y-score (partner→FBXL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POLR3H →	-0.551	-0.578	.009	.005	3	1
UCEC	TRIM9 →	+0.728	+0.601	<.001	.002	3	1
UCEC	AHCY →	-1.287	-0.590	.003	.005	3	1
UCEC	CHRDL1 →	+1.404	+0.638	.003	.001	3	1
UCEC	ZDHHC15 →	+0.558	+0.453	.003	.004	3	1
UCEC	KATNAL1 →	+1.018	+0.927	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

Exploration

FBXL22 survival (RNA) · tumor vs normal (RNA) · all FBXL22 data types