Across TCGA cell cohorts, FBXL22 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,576 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FBXL22-associated GO terms across cancer lineages are Regulation of protein maturation, Blood coagulation, and Hemostasis. Each is linked with FBXL22 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBXL22-to-partner and partner-to-FBXL22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL22→partner) and Y-score (partner→FBXL22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of protein maturation →	-0.156	-0.670	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Blood coagulation →	-0.139	-0.332	<.001	.002	3	9
BREAST	Hemostasis →	-0.089	-0.603	<.001	<.001	3	9
OESOPHAGUS	Regulation of collagen biosynthetic process →	-0.131	-0.418	.002	.006	3	9
SOFT_TISSUE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.117	+0.453	<.001	.002	3	9
LIVER	Urokinase plasminogen activator signaling pathway →	-1.268	-0.340	.002	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,576 associations by consensus.

Exploration

FBXL22 survival (RNA) · tumor vs normal (RNA) · all FBXL22 data types