FBXL21P

Across TCGA patient cohorts, FBXL21P mutation is significantly associated with the RNA expression of many other genes, with 2,791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FBXL21P-associated genes across cancer lineages are SLC25A18P1, RN7SL210P, and SCARNA21B. Each is linked with FBXL21P in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL21P-to-partner and partner-to-FBXL21P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A18P1 grouped by FBXL21P-low versus FBXL21P-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL21P→partner) and Y-score (partner→FBXL21P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SLC25A18P1 →	+0.066	+5.225	<.001	.001	3	2
SKCM	RN7SL210P →	+0.085	+3.625	<.001	.004	3	2
READ	SCARNA21B →	+0.292	+5.039	.009	.008	3	2
COAD	MIR4710 →	+0.713	+4.602	<.001	.008	3	2
UCEC	CCDC116 →	+0.209	+2.168	<.001	.009	3	2
UCEC	R3HCC1L →	+0.375	+2.095	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,791 associations by consensus.

SLC25A18P1 by FBXL21P expression — SKCM

Explore this box plot interactively →