FBXL20

Across TCGA patient cohorts, FBXL20 protein abundance is significantly associated with the RNA expression of many other genes, with 11,881 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXL20-associated genes across cancer lineages are PIP4K2B, CASC3, and HDAC5. Each is linked with FBXL20 in more than 4 cancer types. Because this analysis shows association rather than direction, both FBXL20-to-partner and partner-to-FBXL20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL20 versus PIP4K2B in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL20→partner) and Y-score (partner→FBXL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIP4K2B →	+0.613	+0.310	<.001	<.001	3	5
LSCC	CASC3 →	+0.599	+0.270	<.001	<.001	3	5
COAD	HDAC5 →	+0.474	+0.380	<.001	<.001	3	4
HNSC	RHOT1 →	+0.577	+0.230	.005	.003	3	4
LSCC	STAT5B →	+0.542	+0.293	<.001	<.001	3	4
LSCC	ZNF252P-AS1 →	+0.359	+0.198	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,881 associations by consensus.

FBXL20 vs PIP4K2B — LSCC

Explore this scatter interactively →