FBXL19

Across TCGA patient cohorts, FBXL19 protein abundance is significantly associated with the RNA expression of many other genes, with 3,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FBXL19-associated genes across cancer lineages are CLNK, C17orf75, and C11orf21. Each is linked with FBXL19 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXL19-to-partner and partner-to-FBXL19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL19 versus CLNK in HNSC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL19→partner) and Y-score (partner→FBXL19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CLNK →	-0.964	-0.463	.002	<.001	3	3
LSCC	C17orf75 →	+0.445	+0.335	.003	<.001	3	2
HNSC	C11orf21 →	-0.461	-0.317	.004	.002	3	2
UCEC	ANLN →	+0.825	+0.350	.004	.001	3	2
UCEC	GSTCD →	+0.424	+0.312	.006	.007	3	2
HNSC	SKAP1 →	-1.281	-0.438	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

FBXL19 vs CLNK — HNSC

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