FBXL17

Across TCGA cell cohorts, FBXL17 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,193 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FBXL17-associated GO terms across cancer lineages are Macroautophagy, Process utilizing autophagic mechanism, and Autophagy. Each is linked with FBXL17 in more than 14 cancer types. Because this analysis shows association rather than direction, both FBXL17-to-partner and partner-to-FBXL17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by FBXL17-low versus FBXL17-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL17→partner) and Y-score (partner→FBXL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.055	+0.875	.005	.005	3	15
SOFT_TISSUE	Process utilizing autophagic mechanism →	+0.067	+1.254	<.001	<.001	3	14
SOFT_TISSUE	Autophagy →	+0.067	+1.254	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.072	+1.289	.001	<.001	3	14
SOFT_TISSUE	Endosomal transport →	+0.055	+0.896	<.001	<.001	3	14
SOFT_TISSUE	Post-Golgi vesicle-mediated transport →	+0.065	+0.965	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,193 associations by consensus.

Macroautophagy by FBXL17 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →