FBXL15

Across TCGA patient cohorts, FBXL15 protein abundance is significantly associated with the RNA expression of many other genes, with 9,443 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FBXL15-associated genes across cancer lineages are MAN2A1, HAVCR2, and CEACAM21. Each is linked with FBXL15 in more than 2 cancer types. Because this analysis shows association rather than direction, both FBXL15-to-partner and partner-to-FBXL15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBXL15 versus MAN2A1 in GBM, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL15→partner) and Y-score (partner→FBXL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAN2A1 →	+0.380	+0.138	.008	.008	3	3
GBM	HAVCR2 →	+0.889	+0.293	<.001	<.001	3	3
GBM	CEACAM21 →	+0.408	+0.157	.004	.002	3	3
COAD	BCL2A1 →	+1.979	+0.473	.003	.004	3	3
GBM	LZTS2 →	+0.373	+0.223	.002	.003	3	2
LUAD	FBXW4 →	+0.366	+0.243	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,443 associations by consensus.

FBXL15 vs MAN2A1 — GBM

Explore this scatter interactively →