FBXL15

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FBXL15 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBXL15-associated genes across cancer lineages are DMRTC2. Each is linked with FBXL15 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBXL15-to-partner and partner-to-FBXL15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTC2 grouped by FBXL15-low versus FBXL15-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBXL15→partner) and Y-score (partner→FBXL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaDMRTC2 →+0.036+4.539<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

DMRTC2 by FBXL15 expression — BLOOD_Leukemia

Box plot of DMRTC2 in FBXL15-low vs FBXL15-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration