FBRSL1

Across TCGA pan-cancer cohorts, FBRSL1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FBRSL1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FBRSL1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FBRSL1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

LUAD, LSCC, and HNSC are the cancer types where FBRSL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	III,IV	0.489	0.961	.010	15	view →
LSCC	OS	Quartile	All	0.924	0.653	.005	8	view →
HNSC	DFS	Tertile	IV	0.776	0.235	.013	3	view →
PDAC	DFS	Median	III,IV	0.122	0.943	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FBRSL1–LUAD (DFS)

Open the LUAD breakdown →