FBP1

Across TCGA pan-cancer cohorts, FBP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FBP1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher FBP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FBP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and COAD are the cancer types where FBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.635	0.373	<.001	73	view →
CCRCC	OS	Quartile	All	0.964	0.709	.002	36	view →
COAD	DFS	Median	III,IV	0.838	1.000	.037	12	view →
GBM	OS	Quartile	All	0.270	0.633	.003	9	view →
HNSC	DFS	Median	IV	0.920	1.000	.028	5	view →
LUAD	OS	Median	III,IV	0.882	0.362	.021	4	view →
LSCC	DFS	Tertile	All	0.864	0.690	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FBP1–PDAC (OS)

Open the PDAC breakdown →