FBP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,687 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBP1-associated genes across cancer lineages are NCKAP1L, PPM1M, and ITGAM. Each is linked with FBP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FBP1-to-partner and partner-to-FBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBP1 versus NCKAP1L in GBM, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBP1→partner) and Y-score (partner→FBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNCKAP1L →+1.017+0.903<.001<.00137
HNSCPPM1M →+0.764+0.858<.001<.00137
OVITGAM →+1.056+0.646.003.00137
GBMTMEM273 →+0.996+0.864<.001<.00137
BRCATNFSF12 →+0.808+0.585<.001<.00137
OVFCN1 →+1.049+0.696<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,687 associations by consensus.

FBP1 vs NCKAP1L — GBM

Per-sample scatter of FBP1 vs NCKAP1L in GBM (Pearson r = 0.76).

Explore this scatter interactively →

Exploration