FBP1

Across TCGA cell cohorts, FBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,291 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FBP1-associated GO terms across cancer lineages are Cellular hyperosmotic salinity response, Hyperosmotic salinity response, and Regulation of endothelial tube morphogenesis. Each is linked with FBP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBP1-to-partner and partner-to-FBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular hyperosmotic salinity response grouped by FBP1-low versus FBP1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBP1→partner) and Y-score (partner→FBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cellular hyperosmotic salinity response →	-0.238	-2.245	<.001	<.001	3	12
LUNG_SCLC	Hyperosmotic salinity response →	-0.238	-2.245	<.001	<.001	3	12
OVARY	Regulation of endothelial tube morphogenesis →	+1.099	+1.693	<.001	<.001	3	8
BREAST	L-glutamine catabolic process →	-0.187	-2.711	<.001	<.001	3	8
LARGE_INTESTINE	Acetylcholine biosynthetic process →	+1.745	+2.232	<.001	<.001	3	8
LARGE_INTESTINE	Positive regulation of arachidonate secretion →	-0.213	-1.765	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,291 associations by consensus.

Cellular hyperosmotic salinity response by FBP1 expression — LUNG_SCLC

Explore this box plot interactively →