FBN3

Across TCGA patient cohorts, FBN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,254 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FBN3-associated proteins across cancer lineages are NRF1, DNMT3A, and EHMT2. Each is linked with FBN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both FBN3-to-partner and partner-to-FBN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBN3 versus NRF1 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FBN3→partner) and Y-score (partner→FBN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NRF1 →	+0.305	+1.287	.001	.004	3	4
BRCA	DNMT3A →	+0.751	+1.259	<.001	<.001	3	4
LSCC	EHMT2 →	+0.246	+0.871	.001	<.001	3	4
BRCA	MSH6 →	+0.618	+1.166	<.001	<.001	3	4
BRCA	NFIB →	+0.741	+1.135	<.001	<.001	3	4
GBM	MORC2 →	+0.376	+1.643	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,254 associations by consensus.

FBN3 vs NRF1 — OV

Explore this scatter interactively →