FBN3

Across TCGA cell cohorts, FBN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,633 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FBN3-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Positive regulation of double-strand break repair, and Cell cycle phase transition. Each is linked with FBN3 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBN3-to-partner and partner-to-FBN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by FBN3-low versus FBN3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBN3→partner) and Y-score (partner→FBN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA metabolic process →	+0.074	+1.561	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.076	+0.940	<.001	.004	3	11
BONE	Cell cycle phase transition →	+0.095	+2.035	<.001	<.001	3	10
OVARY	Regulation of myoblast fusion →	+0.119	+1.655	<.001	<.001	3	10
BONE	Positive regulation of DNA repair →	+0.091	+1.920	<.001	<.001	3	10
BONE	Regulation of DNA repair →	+0.070	+1.585	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,633 associations by consensus.

Positive regulation of DNA metabolic process by FBN3 expression — BONE

Explore this box plot interactively →