FBN2

Across TCGA cell cohorts, FBN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,685 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FBN2-associated GO terms across cancer lineages are Nuclear transport, Bone trabecula morphogenesis, and Nucleocytoplasmic transport. Each is linked with FBN2 in more than 10 cancer types. Because this analysis shows association rather than direction, both FBN2-to-partner and partner-to-FBN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by FBN2-low versus FBN2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBN2→partner) and Y-score (partner→FBN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear transport →	+0.064	+2.862	.006	<.001	3	9
LIVER	Bone trabecula morphogenesis →	-0.219	-2.658	.009	.004	1	11
OESOPHAGUS	Nucleocytoplasmic transport →	+0.064	+2.862	.006	<.001	3	9
OESOPHAGUS	Protein folding →	+0.073	+2.050	<.001	.002	3	9
BREAST	Protein K11-linked ubiquitination →	+0.079	+1.664	.002	.003	3	8
OESOPHAGUS	Nucleic acid transport →	+0.104	+1.947	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,685 associations by consensus.

Nuclear transport by FBN2 expression — OESOPHAGUS

Explore this box plot interactively →