FBLN5

Across TCGA cell cohorts, FBLN5 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FBLN5-associated genes across cancer lineages are UCMA, MSGN1, and TBC1D21. Each is linked with FBLN5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FBLN5-to-partner and partner-to-FBLN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCMA grouped by FBLN5-low versus FBLN5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN5→partner) and Y-score (partner→FBLN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UCMA →	+0.060	+3.926	<.001	.003	3	2
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
LARGE_INTESTINE	C14orf180 →	+0.176	+3.155	<.001	.008	3	1
LARGE_INTESTINE	OR6Q1 →	+0.015	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

UCMA by FBLN5 expression — BLOOD_Leukemia

Explore this box plot interactively →