FBLN2

Across TCGA patient cohorts, FBLN2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,888 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible FBLN2-associated genes across cancer lineages are COL5A2, FAP, and MYL9. Each is linked with FBLN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both FBLN2-to-partner and partner-to-FBLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FBLN2 versus COL5A2 in BRCA, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN2→partner) and Y-score (partner→FBLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL5A2 →	+1.543	+0.810	<.001	<.001	3	10
BRCA	FAP →	+1.318	+0.870	<.001	<.001	3	10
COAD	MYL9 →	+1.209	+0.637	<.001	<.001	3	9
OV	ASPN →	+2.070	+0.915	.001	.002	2	10
GBM	COL1A1 →	+2.041	+0.796	<.001	<.001	3	9
CCRCC	PDGFRB →	+1.352	+0.958	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,888 associations by consensus.

FBLN2 vs COL5A2 — BRCA

Explore this scatter interactively →