FBLN2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FBLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,024 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FBLN2-associated GO terms across cancer lineages are Endoplasmic reticulum to Golgi vesicle-mediated transport, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of post-translational protein modification. Each is linked with FBLN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both FBLN2-to-partner and partner-to-FBLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum to Golgi vesicle-mediated transport grouped by FBLN2-low versus FBLN2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FBLN2→partner) and Y-score (partner→FBLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINEndoplasmic reticulum to Golgi vesicle-mediated transport →+0.059+1.658<.001.002312
UPPER_AERODIGESTIVE_TRACTNegative regulation of syncytium formation by plasma membrane fusion →+0.095+2.473.002.001310
BREASTRegulation of post-translational protein modification →+0.043+1.999<.001.001310
BONEProtein folding →+0.070+2.998.002<.001210
UPPER_AERODIGESTIVE_TRACTNegative regulation of myoblast fusion →+0.093+2.473.003.00139
UPPER_AERODIGESTIVE_TRACTRegulation of syncytium formation by plasma membrane fusion →+0.104+2.489<.001.00839
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,024 associations by consensus.

Endoplasmic reticulum to Golgi vesicle-mediated transport by FBLN2 expression — SKIN

Box plot of Endoplasmic reticulum to Golgi vesicle-mediated transport in FBLN2-low vs FBLN2-high samples in SKIN.

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Exploration