Across TCGA patient cohorts, FAT4 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,473 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAT4-associated proteins across cancer lineages are GNPDA2, PRKG1, and RBSN. Each is linked with FAT4 in more than 7 cancer types. Because this analysis shows association rather than direction, both FAT4-to-partner and partner-to-FAT4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT4→partner) and Y-score (partner→FAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GNPDA2 →	+0.373	+0.931	<.001	<.001	3	8
UCEC	PRKG1 →	+0.908	+0.746	<.001	<.001	3	8
LUAD	RBSN →	+0.240	+0.801	<.001	<.001	3	8
PDAC	SEPTIN4 →	+0.573	+0.435	<.001	<.001	3	8
UCEC	SORBS3 →	+0.426	+0.613	<.001	<.001	3	8
UCEC	SYNPO2_S363 →	+1.288	+0.670	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,473 associations by consensus.

Exploration

FAT4 survival (RNA) · tumor vs normal (RNA) · all FAT4 data types