FAT3

Across TCGA patient cohorts, FAT3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,279 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAT3-associated genes across cancer lineages are MINDY1, SCD5, and HBA2. Each is linked with FAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAT3-to-partner and partner-to-FAT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAT3 versus MINDY1 in OV, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT3→partner) and Y-score (partner→FAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MINDY1 →	+0.879	+0.893	.004	.005	3	2
GBM	SCD5 →	+0.896	+0.482	<.001	<.001	3	2
OV	HBA2 →	+1.936	+0.838	.001	<.001	3	2
GBM	PGLYRP1 →	+0.421	+0.292	<.001	<.001	3	2
LUAD	AAMP →	+0.393	+2.361	.002	<.001	3	2
LUAD	MAP1B →	-1.431	-2.619	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,279 associations by consensus.

FAT3 vs MINDY1 — OV

Explore this scatter interactively →