FAT3

Across TCGA cell cohorts, FAT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,945 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FAT3-associated GO terms across cancer lineages are Regulation of mRNA processing, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with FAT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both FAT3-to-partner and partner-to-FAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by FAT3-low versus FAT3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT3→partner) and Y-score (partner→FAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of mRNA processing →	+0.080	+1.427	.008	.001	2	11
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.598	<.001	.006	3	10
OVARY	Negative regulation of myoblast fusion →	+0.101	+1.071	<.001	.002	2	11
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.085	+1.481	<.001	<.001	3	10
OVARY	Cytoplasmic translation →	+0.080	+1.178	.001	<.001	3	9
OVARY	Regulation of translational initiation →	+0.086	+1.114	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,945 associations by consensus.

Regulation of mRNA processing by FAT3 expression — BONE

Explore this box plot interactively →