FAT2

Across TCGA patient cohorts, FAT2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,485 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FAT2-associated genes across cancer lineages are KLF15, BMI1, and FAM83A. Each is linked with FAT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FAT2-to-partner and partner-to-FAT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAT2 versus KLF15 in HNSC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT2→partner) and Y-score (partner→FAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLF15 →	-0.898	-0.629	<.001	<.001	3	4
OV	BMI1 →	-0.614	-0.593	<.001	<.001	3	4
OV	FAM83A →	+1.283	+0.486	.003	.001	3	3
LSCC	PI3 →	+2.098	+0.718	<.001	<.001	3	3
LUAD	JUP →	+0.935	+1.782	.004	<.001	3	3
UCEC	S100A16 →	+1.059	+0.371	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,485 associations by consensus.

FAT2 vs KLF15 — HNSC

Explore this scatter interactively →