FAT1

Across TCGA patient cohorts, FAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,438 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAT1-associated genes across cancer lineages are COL4A1, COL4A2, and POGLUT2. Each is linked with FAT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FAT1-to-partner and partner-to-FAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAT1 versus COL4A1 in OV, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAT1→partner) and Y-score (partner→FAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COL4A1 →	+1.096	+0.381	<.001	<.001	3	7
OV	COL4A2 →	+1.045	+0.375	<.001	<.001	3	6
BRCA	POGLUT2 →	+0.705	+0.329	<.001	<.001	3	6
BRCA	SERPINH1 →	+0.964	+0.328	<.001	<.001	3	6
OV	ITGB1 →	+0.846	+0.595	<.001	<.001	3	6
BRCA	FBLIM1 →	+1.247	+0.458	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,438 associations by consensus.

FAT1 vs COL4A1 — OV

Explore this scatter interactively →