Across TCGA patient cohorts, FASTKD5 mutation is significantly associated with the RNA expression of many other genes, with 2,178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FASTKD5-associated genes across cancer lineages are RNU6-468P, RNVU1-33, and RNA5SP131. Each is linked with FASTKD5 in more than 2 cancer types. Because this analysis shows association rather than direction, both FASTKD5-to-partner and partner-to-FASTKD5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD5→partner) and Y-score (partner→FASTKD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-468P →	+0.476	+4.978	<.001	.005	3	3
LUSC	RNVU1-33 →	+0.486	+4.849	<.001	.002	3	2
LUSC	RNA5SP131 →	+0.545	+5.031	<.001	.002	3	2
LUSC	RNU6ATAC26P →	+0.355	+4.447	.003	.006	3	2
LUSC	UBE2V1P10 →	+0.135	+4.706	<.001	.007	3	2
LUSC	MIR4694 →	+0.415	+5.438	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,178 associations by consensus.

Exploration

FASTKD5 survival (RNA) · tumor vs normal (RNA) · all FASTKD5 data types