FASTKD3

Across TCGA patient cohorts, FASTKD3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,134 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FASTKD3-associated genes across cancer lineages are CLDN24, TRAJ42, and PTGDS. Each is linked with FASTKD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FASTKD3-to-partner and partner-to-FASTKD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FASTKD3 versus CLDN24 in GBM, with a Pearson correlation of -0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD3→partner) and Y-score (partner→FASTKD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CLDN24 →	-0.540	-0.360	.001	.001	3	2
HNSC	TRAJ42 →	-2.031	-0.582	<.001	.001	3	2
HNSC	PTGDS →	-0.792	-0.540	.006	<.001	3	2
HNSC	NUP155 →	+0.915	+0.480	<.001	.003	3	2
HNSC	KCMF1 →	+0.476	+0.416	.003	.007	3	2
HNSC	GNG7 →	-0.557	-0.415	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,134 associations by consensus.

FASTKD3 vs CLDN24 — GBM

Explore this scatter interactively →