FASTKD3

Across TCGA cell cohorts, FASTKD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,549 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible FASTKD3-associated GO terms across cancer lineages are Protein localization to nuclear inner membrane, Meiotic recombination checkpoint signaling, and Positive regulation of mitochondrial translation. Each is linked with FASTKD3 in more than 15 cancer types. Because this analysis shows association rather than direction, both FASTKD3-to-partner and partner-to-FASTKD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nuclear inner membrane grouped by FASTKD3-low versus FASTKD3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD3→partner) and Y-score (partner→FASTKD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein localization to nuclear inner membrane →	+0.213	+0.926	<.001	<.001	3	16
PANCREAS	Meiotic recombination checkpoint signaling →	+0.227	+0.908	<.001	<.001	3	15
BLOOD_Myeloma	Positive regulation of mitochondrial translation →	+0.091	+0.706	.008	.006	2	16
BONE	Regulation of mitochondrial mRNA stability →	+0.131	+0.795	.003	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of meiotic nuclear division →	+0.209	+1.388	<.001	<.001	3	14
BREAST	Regulation of mitotic sister chromatid segregation →	+0.121	+0.685	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,549 associations by consensus.

Protein localization to nuclear inner membrane by FASTKD3 expression — URINARY_TRACT

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