FASTKD1

Across TCGA patient cohorts, FASTKD1 mutation is significantly associated with the RNA expression of many other genes, with 3,009 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FASTKD1-associated genes across cancer lineages are USP9YP2, MIR6085, and RPL7L1P12. Each is linked with FASTKD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both FASTKD1-to-partner and partner-to-FASTKD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by FASTKD1-low versus FASTKD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTKD1→partner) and Y-score (partner→FASTKD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP9YP2 →	+0.009	+4.066	<.001	.003	3	3
LIHC	MIR6085 →	+0.350	+5.447	<.001	.005	3	2
READ	RPL7L1P12 →	+0.112	+4.202	.001	.008	3	2
READ	ANKRD20A6P →	+0.247	+4.925	<.001	.004	3	2
UCEC	KIF13B →	+0.658	+2.222	<.001	<.001	3	2
UCEC	RNA5SP502 →	+0.461	+1.730	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,009 associations by consensus.

USP9YP2 by FASTKD1 expression — UCEC

Explore this box plot interactively →