FASTK

Across TCGA cell cohorts, FASTK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,234 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FASTK-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Establishment of meiotic sister chromatid cohesion, and Cilium movement involved in cell motility. Each is linked with FASTK in more than 15 cancer types. Because this analysis shows association rather than direction, both FASTK-to-partner and partner-to-FASTK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by FASTK-low versus FASTK-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FASTK→partner) and Y-score (partner→FASTK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Pre-mRNA catabolic process →	+0.193	+0.756	<.001	<.001	3	16
SKIN	Establishment of meiotic sister chromatid cohesion →	-0.197	-0.998	.001	<.001	3	14
LARGE_INTESTINE	Cilium movement involved in cell motility →	-0.101	-0.710	<.001	<.001	3	13
URINARY_TRACT	Sperm motility →	-0.121	-0.660	<.001	<.001	3	13
URINARY_TRACT	Flagellated sperm motility →	-0.121	-0.660	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Negative regulation of translational initiation →	+0.096	+0.846	.002	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,234 associations by consensus.

Pre-mRNA catabolic process by FASTK expression — LARGE_INTESTINE

Explore this box plot interactively →