FARSA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FARSA protein abundance is significantly associated with the RNA expression of many other genes, with 9,602 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FARSA-associated genes across cancer lineages are FARSB, FCGR2A, and DSE. Each is linked with FARSA in more than 7 cancer types. Because this analysis shows association rather than direction, both FARSA-to-partner and partner-to-FARSA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FARSA versus FARSB in OV, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARSA→partner) and Y-score (partner→FARSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFARSB →+0.566+0.291<.001<.00138
OVFCGR2A →-1.196-0.340<.001<.00136
OVDSE →-0.739-0.200<.001.00736
GBMPIK3R5 →-1.065-0.244<.001<.00136
UCECFAM20A →-0.806-0.160.003.00335
BRCAC5AR1 →-0.748-0.267<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,602 associations by consensus.

FARSA vs FARSB — OV

Per-sample scatter of FARSA vs FARSB in OV (Pearson r = 0.61).

Explore this scatter interactively →

Exploration