FARSA

Across TCGA cell cohorts, FARSA mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FARSA-associated genes across cancer lineages are SEZ6L, C1QTNF7, and DCSTAMP. Each is linked with FARSA in more than 1 cancer types. Because this analysis shows association rather than direction, both FARSA-to-partner and partner-to-FARSA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEZ6L grouped by FARSA-low versus FARSA-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARSA→partner) and Y-score (partner→FARSA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SEZ6L →	+0.139	+3.409	<.001	.009	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.098	+3.260	<.001	<.001	3	1
LARGE_INTESTINE	DCSTAMP →	+0.102	+2.614	<.001	.005	3	1
LARGE_INTESTINE	TMCO5A →	+0.013	+3.415	<.001	.001	3	1
LARGE_INTESTINE	C4orf47 →	+0.498	+3.371	<.001	.004	3	1
LARGE_INTESTINE	MRC1 →	+0.070	+3.567	.008	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

SEZ6L by FARSA expression — LARGE_INTESTINE

Explore this box plot interactively →