FARP2

Across TCGA patient cohorts, FARP2 mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FARP2-associated genes across cancer lineages are Lck, PDK1_pS241, and RAD51. Each is linked with FARP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FARP2-to-partner and partner-to-FARP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lck grouped by FARP2-low versus FARP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP2→partner) and Y-score (partner→FARP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Lck →	+0.459	+3.025	.003	.019	3	2
COAD	PDK1_pS241 →	-0.185	-2.991	.034	.036	3	2
COAD	RAD51 →	+0.180	+3.008	.028	.019	3	2
COAD	Src_pY527 →	-0.538	-2.991	.008	.036	3	2
COAD	Caspase-7-cleavedD198 →	+1.397	+3.008	<.001	.019	3	2
UCEC	EGFR_pY1068 →	-0.198	-1.184	.008	.022	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Lck by FARP2 expression — COAD

Explore this box plot interactively →