FARP2

Across TCGA pan-cancer cohorts, FARP2 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of FARP2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FARP2 RNA is repressed in tumor relative to normal tissue. In most cancer types FARP2 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, HNSC, and KICH are the cancer types where FARP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FARP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−0.728	<.001	11	view →
HNSC	Male	All	+0.741	<.001	10	view →
KICH	Male	All	−1.120	<.001	8	view →
STAD	Male	II,III,IV	+1.100	<.001	8	view →
LUSC	Male	All	+0.478	<.001	6	view →
KIRC	Male	II,III,IV	−0.474	<.001	6	view →
BRCA	All	II,III,IV	+0.352	<.001	6	view →
CHOL	Male	All	+1.561	<.001	5	view →
ESCA	All	II,III,IV	+0.969	.010	4	view →
PAAD	All	All	+0.585	.004	4	view →
KIRP	All	IV	+0.875	.003	2	view →
LUAD	Male	All	+0.470	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

FARP2–THCA

Open the THCA breakdown →