FARP2

Across TCGA cell cohorts, FARP2 mutation is significantly associated with the RNA expression of many other genes, with 232 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FARP2-associated genes across cancer lineages are MTRNR2L10, SPZ1, and TMEM174. Each is linked with FARP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FARP2-to-partner and partner-to-FARP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L10 grouped by FARP2-low versus FARP2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP2→partner) and Y-score (partner→FARP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MTRNR2L10 →	+0.006	+4.906	<.001	.006	3	1
BREAST	SPZ1 →	+0.020	+3.963	<.001	.003	3	1
BREAST	TMEM174 →	+0.015	+3.672	<.001	.006	3	1
LARGE_INTESTINE	PLA2G3 →	+1.065	+2.215	<.001	.003	3	1
LARGE_INTESTINE	ANKRD54 →	+0.454	+2.129	.002	.007	3	1
LARGE_INTESTINE	POLR2F →	+0.498	+3.252	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 232 associations by consensus.

MTRNR2L10 by FARP2 expression — OESOPHAGUS

Explore this box plot interactively →