FARP1

Across TCGA patient cohorts, FARP1 mutation is significantly associated with the RNA expression of many other genes, with 5,907 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FARP1-associated genes across cancer lineages are GEMIN2, ALKBH1, and PFAS. Each is linked with FARP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FARP1-to-partner and partner-to-FARP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GEMIN2 grouped by FARP1-low versus FARP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FARP1→partner) and Y-score (partner→FARP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GEMIN2 →	+0.479	+2.088	<.001	<.001	3	4
UCEC	ALKBH1 →	+0.399	+2.328	<.001	<.001	3	3
UCEC	PFAS →	+0.447	+2.169	<.001	<.001	3	3
UCEC	UTP11 →	+0.378	+1.597	<.001	<.001	3	3
UCEC	TRAIP →	+0.439	+4.247	<.001	<.001	3	3
UCEC	IGLV3-27 →	+0.875	+1.887	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,907 associations by consensus.

GEMIN2 by FARP1 expression — UCEC

Explore this box plot interactively →