FAR1-IT1

Across TCGA pan-cancer cohorts, FAR1-IT1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated FAR1-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FAR1-IT1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAR1-IT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, MESO, and ACC are the cancer types where FAR1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.721	0.554	<.001	78	view →
MESO	OS	Quartile	All	0.248	0.463	.002	72	view →
ACC	DFS	Tertile	All	0.157	0.570	<.001	41	view →
DLBC	DFS	Median	All	0.579	1.000	.007	27	view →
KIRC	OS	Quartile	All	0.520	0.681	.003	24	view →
PCPG	DFS	Quartile	All	0.602	0.836	.002	22	view →
UCS	OS	Tertile	III,IV	1.000	0.308	.041	18	view →
LIHC	OS	Tertile	III,IV	0.153	0.633	<.001	18	view →
LUAD	OS	Tertile	III,IV	0.300	0.570	.024	17	view →
SKCM	DFS	Tertile	II,III,IV	0.760	0.659	.004	15	view →
THCA	OS	Tertile	IV	0.832	1.000	.035	13	view →
READ	OS	Median	II,III,IV	1.000	0.839	.022	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

FAR1-IT1–HNSC (DFS)

Open the HNSC breakdown →